Product Description

• Endotoxin-free*
• Animal-derived product free
• Available in Bulk
• High Activity
• Glycosylated disulfide-linked homodimer

Xeno-free BMP-4 is expressed in human 293 cells as a disulfide linked homodimeric glycoprotein with an apparent molecular mass of 34 kDa. This cytokine is produced in a serum-free, chemically defined media. The activity of the human cell expressed cytokine is typically higher (2 to 10ng/mL ED50) than the activity reported
for the cytokine expressed in mouse myeloma cells (20 ng/mL ED50) in a bioassay using the ATDC-5 mouse chrondogenic cell line to measure alkaline phophatase production in response to BMP-4.