Z-AAD-R110是颗粒酶B的底物。来自T淋巴细胞和自然杀伤细胞的粒酶B包括通过caspase激活的目标细胞的凋亡和导致线粒体细胞色素C的释放。

Z-AAD-R110 is a substrate for granzyme B. Granzyme B from T lymphocytes and natural killer cells induces apoptosis in target cells by activating caspases and causing mitochondrial cytochrome C release.

• Ful name: Rhodamine 110, bis-(N-CBZ-L-alanyl-L-alanyl-L-aspartic acid amide)
• λ_Ex/λ_Em of end product (R110) = 496/520 nm
• Off-white to pink solid soluble in DMSO
• Store at -20°C and protect from light
• C₅₆H₅₆N₈O₁₇
• MW: 1113.1