概述

• 产品名称
  SB 203580 hydrochloride
• 描述
  p38 MAPK inhibitor; water soluble
• 生物学描述
  Water soluble, cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1 , RIP2 c-Raf and GSK3.
• 纯度
  > 98%

性能

• 化学名称
  4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine hydrochloride
• 分子量
  413.90
• 化学结构
  
• 分子式
  C₂₁H₁₆FN₃OS.HCl
• CAS编号
  869185-85-3
• PubChem识别号
  16760644
• 存放说明
  Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in water to 25 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  Cl.CS(=O)c1ccc(cc1)c2nc(c(n2)c3ccncc3)c4ccc(F)cc4
• 来源

  Synthetic