SkinEthic^TM RHE三维重建表皮模型是由正常人类角质形成细胞在聚碳酸酯膜上经过体外培养而成。该组织模型具有良好的分层和完整结构，其结构和功能与人类的表皮非常接近。它可用于体外皮肤刺激性（OECD TG439 标准模型），皮肤腐蚀性（OECD TG431 标准模型），医疗器械皮肤刺激性，光毒性，遗传毒性，基因、蛋白组学，经皮吸收/渗透性，细菌粘附，DNA损伤等的检测和研究。

SkinEthic^TM RHE is an in vitro Reconstructed Human Epidermis from normal human keratinocytes cultured on an inert polycarbonate filter at the air-liquid interface, in a chemically defined medium. This model is histologically similar to in vivo human epidermis. This model exists at different stages of maturity. The model is widely used in the test and research in vitro of skin irritation (reference model of OECD-TG439), skin corrosion (reference model of OECD-TG431), Skin irritation of medical devices, Phototoxicity, Genotoxcity, OMICS, Permeability, Bacterial adhesion, DNA damage, etc...