E0771、E0771、E0771E0771 小鼠乳腺癌细胞

Cell line name EO771

Synonyms Eo771; E0771; EO 771

Accession CVCL_GR23

Resource Identification Initiative To cite this cell line use: EO771 (RRID:CVCL_GR23)

Comments Characteristics: Belongs to the luminal subtype B; ERalpha-, ERbeta+, PR+ and ErbB2+ (PubMed=32699527).

Miscellaneous: STR profile from personal communication of Rodriguez-Tarduchy Segovia, Gemma.

Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.

Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C57BL/6.

Hierarchy Children:

CVCL_A2HI (EO-NY) CVCL_C9CA (EO771-Luc) CVCL_B0A2 (EO771.lmb)

CVCL_VE17 (EO771E2) CVCL_D8G0 (Ubigene EO771 Ccl5 KO) CVCL_D8G1 (Ubigene EO771 Epha2 KO)

CVCL_D8G2 (Ubigene EO771 Fabp4 KO) CVCL_D8G3 (Ubigene EO771 Pik3ca KO)

Sex of cell Female

Category Cancer cell line

STR profile Source(s): Direct_author_submission

Markers:

Mouse STR 1-1 17,18,19

Mouse STR 1-2 20,22

Mouse STR 2-1 16,18

Mouse STR 3-2 14,15

Mouse STR 4-2 21.3,22.3,24.3

Mouse STR 5-5 17,21,22

Mouse STR 6-4 18,19,20,21

Mouse STR 6-7 15,16

Mouse STR 7-1 25.2,26,26.2

Mouse STR 8-1 16

Mouse STR 11-2 15.3,16.3

Mouse STR 12-1 17,18

Mouse STR 13-1 17,18

Mouse STR 15-3 22.3,23.3

Mouse STR 17-2 15,16,17

Mouse STR 18-3 16,18

Mouse STR 19-2 13

Mouse STR X-1 27,29

Run an STR similarity search on this cell line

Publications

PubMed=16312045

Ewens A., Mihich E., Ehrke M.J.

Distant metastasis from subcutaneously grown E0771 medullary breast adenocarcinoma.

Anticancer Res. 25:3905-3915(2005)

PubMed=24391448; DOI=10.7150/ijbs.6309; PMCID=PMC3879588

Wang S.-H., Lu L., Fan Y.-Y., Wicha M.S., Cao Z.-Y., Chang A.E., Xia J.-C., Baker J.R. Jr., Li Q.

Characterization of a novel transgenic mouse tumor model for targeting HER2+ cancer stem cells.

Int. J. Biol. Sci. 10:25-32(2013)

PubMed=32699527; DOI=10.1186/s12935-020-01418-1; PMCID=PMC7372867

Le Naour A., Koffi Y., Diab M., Le Guennec D., Rouge S., Aldekwer S., Goncalves-Mendes N., Talvas J., Farges M.-C., Caldefie-Chezet F., Vasson M.-P., Rossary A.

EO771, the first luminal B mammary cancer cell line from C57BL/6 mice.

Cancer Cell Int. 20:328.1-328.13(2020)

PubMed=33026171; DOI=10.1002/cam4.3295; PMCID=PMC7643677

Le Naour A., Rossary A., Vasson M.-P.

EO771, is it a well-characterized cell line for mouse mammary cancer model? Limit and uncertainty.

Cancer Med. 9:8074-8085(2020)