Pan02细胞系;Pan02细胞株;小鼠胰腺癌细胞,Pan02;小鼠胰腺癌细胞,Pan02 Cell line name Panc02 Synonyms Panc-02; Panc 02; Pan02; Pan-02; PAN 02; Panc02-H0 Accession CVCL_D627 Resource Identification Initiative To cite this cell line use: Panc02 (RRID:CVCL_D627) Comments Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264. Disease Mouse pancreatic ductal adenocarcinoma (NCIt: C34041) Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6. Hierarchy Children: CVCL_D7FV (Pan-02-Luc) CVCL_D628 (Panc02-H7) CVCL_A8QL (Panc02-luc) CVCL_E1AG (Ubigene Panc02 Bhlhe40 KO) CVCL_E1AH (Ubigene Panc02 Cd44 KO) Sex of cell Male Category Cancer cell line STR profile Source(s): Ubigene=YC-C067 Markers: Mouse STR 4-2 20.3 Mouse STR 5-5 16,18 Mouse STR 6-4 18 Mouse STR 6-7 17 Mouse STR 12-1 17 Mouse STR 15-3 22.3 Mouse STR 18-3 15 Mouse STR X-1 29 Run an STR similarity search on this cell line Publications PubMed=6692374 Corbett T.H., Roberts B.J., Leopold W.R., Peckham J.C., Wilkoff L.J., Griswold D.P. Jr., Schabel F.M. Jr. Induction and chemotherapeutic response of two transplantable ductal adenocarcinomas of the pancreas in C57BL/6 mice. Cancer Res. 44:717-726(1984) PubMed=11558631; DOI=10.1385/IJGC:29:1:37 Wang B.-L., Shi Q., Abbruzzese J.L., Xiong Q.-H., Le X.-D., Xie K.-P. A novel, clinically relevant animal model of metastatic pancreatic adenocarcinoma biology and therapy. Int. J. Pancreatol. 29:37-46(2001) PubMed=20805420; DOI=10.4049/jimmunol.0902609; PMCID=PMC3693576 Gnerlich J.L., Mitchem J.B., Weir J.S., Sankpal N.V., Kashiwagi H., Belt B.A., Porembka M.R., Herndon J.M., Eberlein T.J., Goedegebuure P., Linehan D.C. Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer. J. Immunol. 185:4063-4071(2010) PubMed=21720167; DOI=10.1159/000329413 Partecke L.I., Sendler M., Kaeding A., Weiss F.U., Mayerle J.V., Dummer A., Nguyen T.D., Albers N., Speerforck S., Lerch M.M., Heidecke C.-D., von Bernstorff W., Stier A. A syngeneic orthotopic murine model of pancreatic adenocarcinoma in the C57/BL6 mouse using the Panc02 and 6606PDA cell lines. Eur. Surg. Res. 47:98-107(2011) PubMed=22208613; DOI=10.2174/156652412799218868; PMCID=PMC3799885 Wang Y., Zhang Y., Yang J., Ni X., Liu S., Li Z., Hodges S.E., Fisher W.E., Brunicardi F.C., Gibbs R.A., Gingras M.-C., Li M. Genomic sequencing of key genes in mouse pancreatic cancer cells. Curr. Mol. Med. 12:331-341(2012)