LM8细胞LM8细胞LM8;小鼠骨肉瘤细胞

Cell line name DLM8

Synonyms Dunn LM8; LM8

Accession CVCL_6669

Resource Identification Initiative To cite this cell line use: DLM8 (RRID:CVCL_6669)

Comments Characteristics: Highly metastatic to lung (PubMed=9579581).

Doubling time: 13 hours (PubMed=9579581).

Omics: Transcriptome analysis by microarray.

Derived from site: In situ; Bone; UBERON=UBERON_0002481.

Disease Mouse osteosarcoma (NCIt: C24021)

Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)

Breed/subspecies: C3H/HeJ.

Hierarchy Parent: CVCL_W629 (Dunn osteosarcoma)

Children:

CVCL_D6BZ (HyCyte LM8 KO-mFgl2) CVCL_RL04 (Luc-LM8)

Sex of cell Female

Category Cancer cell line

Publications

PubMed=9579581; DOI=10.1002/(SICI)1097-0215(19980504)76:3<418::AID-IJC21>3.0.CO;2-5

Asai T., Ueda T., Itoh K., Yoshioka K., Aoki Y., Mori S., Yoshikawa H.

Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung.

Int. J. Cancer 76:418-422(1998)

PubMed=26320182; DOI=10.18632/oncotarget.5177; PMCID=PMC4745740

Ren L., Mendoza A., Zhu J., Briggs J.W., Halsey C., Hong E.S., Burkett S.S., Morrow J.J., Lizardo M.M., Osborne T., Li S.Q., Luu H.H., Meltzer P.S., Khanna C.

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.

Oncotarget 6:29469-29481(2015)

PubMed=26018200; DOI=10.1007/s11999-015-4362-2; PMCID=PMC4746149

Aanstoos M.E., Regan D.P., Rose R.J., Chubb L.S., Ehrhart N.P.

Do mesenchymal stromal cells influence microscopic residual or metastatic osteosarcoma in a murine model?

Clin. Orthop. Relat. Res. 474:707-715(2016)