Description

Cayman’s experienced medicinal chemists, structural biologists, and biochemists possess the skills to accelerate your preclinical drug discovery programs with our hit-to-lead optimization services.

Custom Synthesis & Parallel Library Generation
Our medicinal chemists perform iterative library design and synthesis using parallel medicinal chemistry. Virtual library enumeration with predicted in silico property calculations facilitates the generation of small, focused libraries (20-100 compounds) to quickly learn the SAR around lead templates.

SAR & Lead Optimization
Identify, prioritize, and optimize lead candidates leveraging our expertise in SBDD, organic synthesis, and activity screening. Identify key interactions, model pharmacophores, enumerate hits, and predict binding, physicochemical, and ADME/tox properties.

Item	Hit-to-Lead Optimization
Company	Cayman Chemical
Price	Get QuoteGet Quote
Catalog Number	Custom