Description

With Cayman Contract Services, your lipidomics study is in the hands of scientists who have several decades of collective experience in lipid synthesis, purification, and characterization. Cayman’s lipid analysis laboratories are equipped with state-of-the-art chromatography/mass spectrometry systems and data analysis software.

Cayman offers targeted lipidomics for quantitative analysis of eicosanoids, phospholipids, endocannabinoids, sphingolipids, SCFAs, and more.

Targeted lipidomics enables the focused analysis of a known collection of lipids. Precise method development allows for the inclusion of equal amounts of isotope-labeled or odd-chain internal standards selected from customizable lipid panels. Lipids from each sample are extracted using standardized protocols and analyzed by LC-MS/MS using analyte-specific collision-induced mass transitions from the molecular ion (or, in some cases, from a known adduct) to a characteristic fragment ion. Analyte concentrations are determined from calibration curves prepared from authentic standards, when available, or surrogate standards when necessary. This approach is especially useful for quantifying lipids present at low levels in samples, such as endogenous bioactive lipids (e.g., prostaglandins, leukotrienes, or endocannabinoids). Standard statistical analysis tools can reveal changing trends in lipid species among experimental groups, which can be visualized with a heat map or other available graphical tools.

Targeted Lipid Panels

Maximize data from precious samples with established targeted lipid panels offering the sensitivity, efficiency, and specificity needed to identify and quantify biologically relevant lipids.

• Eicosanoids and Oxylipins
• Sphingolipids
• Endocannabinoids and Endocannabinoid-like Lipids
• Urinary Lipid Metabolites
• Cholesterol Esters
• Short-Chain Fatty Acids
• Phospholipids

Item	Targeted Lipidomics and Absolute Quantitation
Company	Cayman Chemical
Price	Get QuoteGet Quote
Catalog Number	Custom