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98.0% up by HPLC Dexamethasone Sodium Phosphate 55203-24-2
单价 面议对比
询价 暂无
发货 全国
品牌 Sinoway Industrial Co. Ltd
过期 长期有效
更新 2025-08-13 19:00
 
详细信息

Grade: Pharmaceutical Grade

Factory Location: Xiamen

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

Monthly Production Capacity: 10tons/year

Contract Manufacturing: CRO,CMO

Packaging Information: 25kg/bag

Delivery Lead Time: 7 days after payment

Sample Provided: yes

Payment Terms: L/C

Product Information

 

Product name

Dexamethasone Sodium Phosphate

CAS No.

55203-24-2

Molecular Formula

C22H28FNa2O8P

Molecular Weight

516.405

Quality Standard

98% up by HPLC, CEP, EP, USP

Appearance

White to slightly yellow crystalline powder

 

COA

 

Test Items

Specifications

Results

Appearance

White to slightly yellow crystalline powder, free from visible evidence of contamination, very hygroscopic.

White powder

 

 

Identification

A. The RF value of the principal spot obtained from the test solution corresponds to that obtained from the standard solution.

Conforms

B. The residue from the ignition of it meets the requirements of the tests for Phosphate and for Sodium.

Conforms

Assay (on anhydrous and solvent free basis)

97.0% - 102.0%

98.61%

Limit of phosphate ions

1.0%

0.03%

Water

16.0%

3.54%

Residual solvents

Acetone  5000ppm

9ppm

Methanol  3000ppm

270ppm

Alcohol content

 8.0%

Not detected

Chromtographic purity

Any individual impurity  1.0%

0.20%

Total impurities  2.0%

0.40%

Limit of free dexamethasone

1.0%

<0.05%

Specific rotation

+74°~ +82°

+79°

pH

7.7 ~10.5

8.57

Microbial Limit

Aerobic Bacteria  1000cfu/g

< 10cfu/g

 

Mold and Yeast  100cfu/g

< 10cfu/g

 

E.Coli can not be detected

Not detected

Bacterial Endotoxin

<1.2EU/mg

<0.25EU/mg

Conclusion

It conforms to all the requirements of USP36.

 

Usage

 

Basic Information

Dexamethasone Sodium Phosphate is a long-acting glucocorticoid drug. This drug belongs to the class of adrenocortical hormones and possesses anti-inflammatory, anti-allergic, anti-shock, and immunosuppressive effects.

 

Indications

Dexamethasone Sodium Phosphate is primarily indicated for the treatment of the following conditions:

(1) Allergic and autoimmune inflammatory diseases: Including connective tissue diseases, active rheumatic diseases, rheumatoid arthritis, systemic lupus erythematosus, severe bronchial asthma, severe dermatitis, ulcerative colitis, etc.

(2) Hematologic disorders: Such as acute leukemia and comprehensive treatment of malignant lymphoma

(3) Severe infections and intoxications: As an adjunctive therapy

(4) Special applications: Alleviation of cerebral edema caused by malignant tumors, certain pregnancy complications (e.g., promotion of fetal lung maturity), etc.