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99% up by HPLC, GMP Penciclovir 39809-25-1
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更新 2025-08-13 23:38
 
详细信息

Grade: Pharmaceutical Grade

Factory Location: Xiamen, Fujian

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

Monthly Production Capacity: 1000kg

Packaging Information: 25kg/drum 1kg/bottle

Delivery Lead Time: 7 days after payment

Sample Provided: yes

Payment Terms: L/L

Product Information

 

Product name

Penciclovir

CAS No.

39809-25-1

Molecular Formula

C10H15N5O3

Molecular Weight

253.117

Quality Standard

99% up, GMP

Appearance

White or pale yellow powder

 

COA of Penciciovir

 

ITEMS

SPECIFICATIONS

RESULTS

Appearance

White or pale yellow crystalline powder

 Complies

PH

5.5 to 7.5

 6.5

Chloride

Not more than 0.015%

Complies

Related substances

Total impurities

 

Not more than 1.0%

Complies

Loss on drying

Not more than 0.5%

Complies

Residue on ignition

Not more than 0.1%

Complies

Heavy metals

Not more than 0.002%

Complies

Assay

Not less than 99.0%,calculated on dried basis

99.6%

Conclusion

Complies with the specification

 

Usage

 

Function of Penciciovir

Penciclovir is a nucleoside antiviral drug, which has inhibitory effect on type I and type II herpes simplex virus in vitro. In virus-infected cells, viral thymidine kinase phosphorylates penciclovir to penciclovir monophosphate, and cell kinase converts penciclovir monophosphate to penciclovir triphosphate. In vitro experiments show that penciclovir triphosphate and deoxyguanosine triphosphate competitively inhibit herpes simplex virus polymerase, thereby selectively inhibiting herpes simplex virus DNA synthesis and inhibition. Therefore, penciclovir is suitable for the treatment of a variety of herpes virus infections. It has the characteristics of low toxicity and high virus sensitivity. Penciclovir has low oral absorption and is often used for topical administration. Famciclovir is a prodrug of penciclovir and is well absorbed orally.