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Sigma货号H7379人Hemoglobin血红蛋白136
单价 $724.74对比
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品牌 sigma
过期 长期有效
更新 2025-08-12 15:47
 
详细信息

Sigma货号H7379人Hemoglobin血红蛋白13611631389上海睿安生物

一般描述

血红蛋白是红细胞的主要成分,也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34%。由于它能够将氧从肺部输送到身体组织,促进二氧化碳的返回转运,因此血红蛋白是脊椎动物最重要的呼吸蛋白。
形式:lyophilized powder

应用:血红蛋白被用于开发检测视黄醇结合蛋白的快速酶免疫分析法。它也被内皮源性舒张因子用于抑制人血小板反应性。

包装:1g、5g、10g in poly bottle.

生化/生理作用

Fe2+/Fe3+平衡是血液氧合的生理指标。脱氧血红蛋白通过将亚硝酸盐还原为NO(一种血管舒张剂,可促进血液流向缺氧组织)来辅助反馈回路。
氧气转运蛋白,NO清除剂

注意:由于天然血红蛋白在空气中容易氧化,因此这些制剂可能主要是高铁血红蛋白。

 

同行评审论文

Hemoglobin β93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell.Chiao-Wang Sun et al.Circulation, 139(23), 2654-2663 (2019-03-25)Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be essential for export of nitric oxide (NO) bioactivity by the red blood cell (RBC) toExploring the possibilities of infrared spectroscopy for urine sediment examination and detection of pathogenic bacteria in urinary tract infections.Mieke Steenbeke et al.Clinical chemistry and laboratory medicine, 58(10), 1759-1767 (2020-07-11)Objectives In this study, the possibilities of Fourier-transformed infrared spectroscopy (FTIR) for analysis of urine sediments and for detection of bacteria causing urinary tract infections (UTIs) were investigated. Methods Dried urine specimens of control subjects and patients presenting with variousGenetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin.Nai-Jia Huang et al.Nature communications, 8(1), 423-423 (2017-09-06)A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs. Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surfaceElectrochemical sensor for rapid determination of fibroblast growth factor receptor 4 in raw cancer cell lysates.Rebeca M Torrente-Rodríguez et al.PloS one, 12(4), e0175056-e0175056 (2017-04-05)The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic microcarriers (HOOC-MBs)Measurement of S-glutathionylated proteins by HPLC.Daniela Giustarini et al.Amino acids, 54(4), 675-686 (2021-06-16)S-glutathionylated proteins (G_SSP), i.e., protein-mixed disulfides with glutathione (GSH), are considered a suitable biomarker of oxidative stress. In fact, they occur within cells at low level and their concentration increases markedly under pro-oxidant conditions. Plasma is something different, since it

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