Grade: Pharmaceutical Grade

Factory Location: hangzhou

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

Monthly Production Capacity: 500kg/y

Contract Manufacturing: CRO,CMO

Packaging Information: on discussion

Delivery Lead Time: on discussion

Sample Provided: yes

Payment Terms: L/C T/Torothers

Appearance:

Light-Yellow Crystalline Powder

Molecular Weight:

446.9

Density:

1.322g/cm³

Boiling Point:

586.8 °C at 760 mmHg

Melting Point:

119-120

Flash Point:

308.7 °C

Refractive index:

1.621

Biological Activity:

Orally active, selective inhibitor of EGFR tyrosine kinase (IC 50 = 23-79 nM). Shows minimal activity against ErbB2, KDR, c-flt, PKC, MEK and ERK-2. Blocks EGFR autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts.

Usage:

An antineoplastic