Description

> 100,000 Different GPCR Binding Motifs

• With over 100,000 different GPCR binding motifs, unlock the discovery of antibodies to this difficult-to-target class.

GPCRS ARE HARD-TO-DRUG

• 30-50% of current drug targets are GPCRs but there are only 2 FDA approved antibodies

• Current antibody drug development methods do not work

• Random mutagenesis libraries are too inefficient to explore the effective sequence space

SYNTHETIC LIBRARY ADVANTAGE

• No immunization required

• Synthetic mAb libraries focus on effective sequence space

• Simultaneous screening against multiple targets