Grade: Pharmaceutical Grade

Factory Location: Shandong

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

Monthly Production Capacity: 100kg

Contract Manufacturing: CRO,CMO

Packaging Information: 5KG/BAG

Delivery Lead Time: 15days

Sample Provided: yes

Payment Terms: T/T

Application of Desloratadine

1.Desloratadine Application used for Medical Purpose

2. Desloratadine Application used for Food Additives Food Additives.

3.Desloratadine Application used for cosmetic grade

Function of Desloratadine

1. Highly effective in the treatment of loratadine, H1 binds specifically to the H1 receptor, which has the strongest bindingability to the H1 receptor, and has a significant anti receptor effect. It was 4 times more potent than histamine in inhibitinghistamine induced mouse foot swelling. Desloratadine inhibits inflammatory cytokines from stimulation at nanomolar levelsof human mast cells and basophils release, such factors including IL-3, IL-6, TNF- alpha, GM-CSF, the inhibition ratio ofcetirizine

 2. rapid onset, persistent efficacy of loratadine itself has activity, good absorption, onset time of less than 30min. After oraladministration, the maximum plasma concentration was about 3h, and the Cmax was 3.98 ng / mL-1 at a single dose of H-1, and the clearance rate was from 114 to 201L. A study of clinical onset time in patients with allergic rhinitis as theobject of proof, desloratadine than antihistamine effect existing faster, the average onset time of 28.45min, and 1H ofdesloratadine and mizolastine, cetirizine is 2h. Half life is about 24h, and the effect is lasting..