Grade: Pharmaceutical Grade

Factory Location: Shandong

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

Monthly Production Capacity: 100kg

Contract Manufacturing: CRO,CMO

Packaging Information: 5kg/drum

Delivery Lead Time: 15days

Sample Provided: yes

Payment Terms: L/C

Name:   Topiroxostat

Synonyms:   FYX051
                     Topiroxostat
                     Topiroxostat,FYX-051
                     5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole
                     Topiroxostat5-(2-Cyano-4-pyridyl)-3-(4-pyridyl)-1,2,4-triazole
                     4-[5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile
                     2-Pyridinecarbonitrile,4-[5-(4-pyridinyl)-1H-1,2,4-triazol-3-yl]-
                     Topiroxostatimpurty

CAS:   577778-58-6

Molecular Formula:   C13H8N6

Molar Mass:   248.24

Density:   1.45±0.1 g/cm3(Predicted)

Boling Point:   594.7±60.0 °C(Predicted)

Use:   Topilast has a competitive blocking effect on xanthine oxidoreductase, thereby inhibiting uric acid production. It has no blocking effect on other pyrimidine purine metabolizing enzymes, and shows selective blocking effect on xanthine oxidoreductase. Topilast has a significant inhibitory effect on both oxidized and reduced XOR, so its effect of reducing uric acid is more powerful and lasting. Therefore, this product can be used to treat chronic Hyperuricemia of gout.