重组人白介素15，Recombinant Human Interleukin-15
货号：200-15-10ug

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.  IL-15 exerts its biological activities primarily on T cells.  It is also essential in the development, survival and activation of NK cells.  Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I.  Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.  Recombinant Human IL-15 is a 12.9 kDa protein consisting of 115 amino acid residues.

Source: E.coli

 

 

Synonyms: Interleukin-15, IL-T

 

 

AA Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS

 

 

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

 

 

Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of CTLL-2 cells was found to be ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁶ units/mg.

This product has been tested against the WHO standard. International Unit information can be found here.

 

Calculated Molecular Weight: 12.9 kDa

 

 

Accession Number: P40933

 

 

Gene ID: 3600

 

 

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)