Grade: Pharmaceutical Grade

Factory Location: SHAANXI

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Middle East

Monthly Production Capacity: 500kg

Contract Manufacturing: CRO

Packaging Information: As your requirements

Delivery Lead Time: 7-10days

Sample Provided: yes

Payment Terms: T/T

Gentiopicroside is a natural secoiridoid glycoside from gentian species of medicinal plants . It has exhibited a variety of pharmacological activities including hepatoprotective, anti-inflammatory, antinociceptive and smooth muscle relaxing activities .

In one study, the effects of Gentiopicroside on BLM-induced pulmonary fibrosis were investigated in mice. The results demonstrated that administration of Gentiopicroside significantly decreased the contents of TNF-α and IL-1β in BALF of mice. HYP and TGF-β1 in lung tissues also decreased after Gentiopicroside treatment. The alveolar epithelial cells and TGF-β1 could be the main target cells and molecules of Gentiopicroside on BLM-induced PF. Gentiopicroside may also has the potential in combination with nintedanib or pirfenidone in treatment of PF to synergize the therapeutic effects and minimize the adverse effects, but this needs further investigation.