Grade: Pharmaceutical Grade
Factory Location: xi’an , shaanxi,China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe
Monthly Production Capacity: 500kg
Contract Manufacturing: CRO
Packaging Information: As your requirements
Delivery Lead Time: 6-10days
Sample Provided: yes
Payment Terms: T/T
Product Name:Yohimbine hydrochloride
CAS Number : 65-19-0
Molecular Weight :390.904
Molecular Formula:C21H27ClN2O3
Yohimbine hydrochloride is an α2-adrenergic receptor antagonist and increases the firing rate of the locus coeruleus with a resultant increase in sympathetic outflow (Redmond, 1987). Oral and intravenous yohimbine causes an increase in MHPG and blood pressure in healthy human subjects (Charney et al., 1982d; Goldberg et al., 1986). Depressed patients demonstrate an increased cortisol and blood pressure response to intravenous yohimbine compared with healthy subjects, while plasma MHPG is not significantly different between the two groups of subjects (Heninger et al., 1988). The effects of acute or chronic antidepressant treatments on the neuroendocrine or behavioural responses to yohimbine in depressed patients have not been studied.