Grade: Pharmaceutical Grade

Factory Location: anji Huzhou city china

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia

Monthly Production Capacity: 100gm

Packaging Information: 200mg/500mg/1g/10g/50g/100mg per package

Delivery Lead Time: 7 days after order confirmed

Sample Provided: yes

Payment Terms: T/T

Factory Supply 99% Synthetic Liraglutide Powder Peptide API CAS NO 204656-20-2 

 

Introduction:

Liraglutide is a long-acting, fatty acylated glucagon-like peptide-1 (GLP-1) analog administered subcutaneously, with antihyperglycemic activity. Liraglutide's prolonged action and half-life of 11-15 hours are attributed to the attachment of the fatty acid palmitic acid to GLP-1 that reversibly binds to albumin. Albumin binding protects liraglutide from immediate degradation and elimination and causes GLP-1 to be released from abumin in a slow and consistent manner. This agent may cause thyroid C-cell tumors and increases the risk of acute pancreatitis.

Liraglutide is a recombinant DNA produced polypeptide analogue of human glucagon-like peptide-1 (GLP-1) which is used in combination with diet and exercise in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. There have been no published reports of hepatotoxicity attributed to liraglutide therapy.

 

Liraglutide is a lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It has a role as a glucagon-like peptide-1 receptor agonist and a neuroprotective agent. It is a lipopeptide and a polypeptide.

 

Fuction &Application:

Liraglutide has the following pharmacological effects:
Protective effect on islet β cells
The effect of reducing body mass
Cardiovascular effects of liraglutide
Protective effect on the liver
Therapeutic effect on Alzheimer's disease (AD)

 

As a novel long-acting glP-1 analogue, liraglutide has 97% sequence homology with human GLP-1, which can bind and activate the GLP-1 receptor. Glp-1 receptor is the target of natural GLP-1, an endogenous intestinal Chemicalbook insulin stimulating hormone, which promotes the proliferation and differentiation of islet β cells, and significantly protects and improves the function of islet β cells. At the same time, liraglutide is simple and convenient to use, can provide 24h blood glucose control once a day, and the risk of hypoglycemia is small, and is expected to become a new drug for the treatment of type 2 diabetes.

 

                                 Certificate of Analysis

Product Name	Liraglutide	Batch No.	210201
Mfg. Date	Feb 22, 2021	Exp. Date	Feb 21, 2023

 

Sequence: His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(palm-gama-Glu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly   molecular formula：C172H265N43O51，   molecular weight：3751.202
Test	Specification	Results
Appearance	White powder	Conforms
Solubility	Soluble in water	Conforms
Purity (HPLC)	NLT 98.0%	99.5%
Acetic Acid	NMT 8%	0.4%
Mass spectrum	3751.3±1.0	3751.8
Peptide content (N%)	NLT80%	94.8%
Wate Content (Karl Fischer）	NMT7.0%	3.8%

 

 

 

 

Storage:In an air tight container,protected from light at temperature2-8℃. Conclusion:the product complies with enterprise standard.

Not for human use without further processing.

Why Choose Us:

 

1.Stable quality, high quality satisfy customer's high grade sourcing request.
2.Competitive price .
3.Correct delivery time promise.
4.Continuous improvement make sure the long-term cooperation.
5.Honest service for your whole sourcing process.

 

Ench Industry is the professional Oxytocin CAS 50-56-6
Welcome your inquiry and cooperation ,feel free to contact with us !

Contact us:
Call us by 008613675847137
Email us at  jayjie@hjy.com
Contact by QQ 1430571263