Recombinant Penaeus aztecus Pen a1

Catalog #: DRA98      Derived From: E.coli  

 

Description: 

Recombinant Penaeus aztecus Pen a1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr284 is expressed with a 6His tag at the C-terminus.

Accession:  Q3Y8M6

Names(Known as): Tropomyosin Pen a 1.0102; Allergen Pen a 1; Tropomyosin Pen a 1; Pen a 1.0102; Penaeus aztecus Pen a1

 

Quality Control:

Mol Mass: 33.7kDa     AP Mol Mass: 38kDa, reducing conditions

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

 

 

Formulation:

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4

 

Shipping:

The product is shipped on dry ice pack.

Upon receipt, store it immediately at the temperature listed below.

 

Storage:

Reconstituted protein solution should be stored at  ≤ -20°C.

 

Purification: 
Affinity purification chromatography.

 

 

Application:
Immunogen, calibrator or standard.

 

Background:

IgE-mediated hypersensitive reactions to ingestion of shellfish are among the most serious forms of food allergies.Pen a 1 from brown shrimp Penaeus aztecus is the only major allergen of shrimp and binds up to 75% of all shrimp-specific IgE antibodies this molecule may be an excellent model for the usage of allergens with reduced IgE antibody-binding capacity for specific immunotherapy.Recombinant Pen a 1 and natural Pen a 1 are structurally and immunologically identical and rPen a 1 may be used as the basis for component-resolved diagnosis and the generation of modified shrimp tropomyosin for allergen-specific immunotherapy.

 

 

FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY