Language
Grade: Pharmaceutical Grade
Factory Location: Henan,China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 20KG
Packaging Information: according the quantity
Delivery Lead Time: in stock
Sample Provided: yes
Payment Terms: T/T, LC, moneygram, western union
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Molecular Formula: |
C32H45BrN2O8 |
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CAS No.: |
97792-45-5 |
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Appearance: |
White solid |
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Assay: |
98%(TLC;HPLC) |
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Synonyms: |
2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-4,8,9-triol deriv. Hydrobromide; Acetyl-10-deoxysepaconitine Hydrobromide |
Applications
·Lappaconitine hydrobromide is a selective blocker of the TTX-sensitive Na+ channels, and does not influence the activation threshold of Na+ channels.
·Hydrobromide salt of (+)-Lappaconitine, a potential antitumor agent agent that induces HL-60 differentiation and apoptosis with analgesic activity as well.
·Lappaconitine hydrobromide is a diterpene alkaloid extracted from roots of Aconitum sinomantanum. It is a non-narcotic central nervous system analgesic. Lappaconitine also has antiarrhythmic and anti-inflammatory effect. Lappaconitine works as an inhibitor of tetrodotoxin-sensitive, voltage-dependent sodium channels. On the other hand, lappaconitine is reported as an organocatalyst for asymmetric α-hydroxylation of β-keto esters.
