Waters recommends you filter buffers and samples using a 0.2µm filter prior to using ACQUITY UPLC™ BEH columns. Filtration protects the columns and instrument components from a build-up of particulate matter, improving column lifetime and minimizing system downtime. The ACQUITY UPLC™ column In-line filter kit comes complete with the holder and five 0.2µm stainless steel replacement filters. You can order a a package of five replacement filters using Part Number 700002775 which will work with the in-line filter kit.