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SB202190，p38 MAPK抑制剂

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杭州环特生物科技股份有限公司
17364531293 0571-83782130
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  • Brand  新环检测(NewHunter Testing)
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杭州环特生物科技股份有限公司

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Last Updated 2025-08-12 14:17

SB202190，p38 MAPK抑制剂

SB202190是一种有效的MAPK抑制剂，可特异地抑制p38 α和p38 β（IC50值分别为50 nM和100 nM），通过与ATP竞争p38上的相同结合部位而产生抑制效应。SB202190能有效地激活THP-1和MV4-11细胞的生长。此外，SB202190还增加了C-Raf和ERK的磷酸化，提示Raf-MEK-MAPK通路的激活参与了SB202190诱导的细胞生长。
Company Name 杭州环特生物科技股份有限公司
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Business Scope 产品功效与安全性评价，原料配方筛选验证，药效评价与药物筛选，毒理药理评价，临床前研究，斑马鱼基因编辑，类器官培养与试剂售卖，小鼠实验平台，科研课题研究，斑马鱼实验室建设，斑马鱼养殖系统与技术授权培训等。
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