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青链霉素混合液100X KGL2303-100

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江苏凯基生物技术股份有限公司
025-52880811
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Last Updated 2025-08-12 14:33

青链霉素混合液100X KGL2303-100

青霉素-链霉素(Penicillin-Streptomycin Solution)混合液,通常也被称为“双抗”,是体外培养中为预防微生物污染最常用的抗生素,常配制成100倍浓度母液使用。其中,青霉素能够干扰细菌细胞壁的合成,对革兰阳性菌特别有效;而链霉素能够与细菌核糖体30S亚单位结合,抑制细菌蛋白质的合成,对革兰氏阴性菌和革兰氏阳性菌均有效,但对革兰氏阴性菌特别有效。

青霉素和链霉素联合使用可以预防绝大部分的细菌污染,但青霉素溶液对温度和酸碱度较为敏感,室温易降解,需冷冻保存,PH 6.0~6.5时最为稳定;而链霉素则相对稳定,PH 5.0~7.5时最为稳定。 


实验类型:抗生素

酚红:No

性质说明:透明液体

保存条件:-20℃避光保存一年 

部分引用文献:

【1】 Microfluidic intestinal organoid-on-a-chip uncovers therapeutic targets by recapitulating oxygen dynamics of intestinal IR injury,10.1016/j.bioactmat.2023.07.001,Bioactive Materials,2023-07-21,IF=18.9,南京大学医学院附属金陵医院(中国人民解放军东部战区总医院),.

【2】 Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a,10.1038/s41467-022-32169-4,Nature Communications,2022-08-05,IF=17.694,中山大学附属第三医院,.

【3】 Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products,10.1021/acsnano.3c04726,ACS Nano,2023-07-05,IF=17.1,药物化学生物学全国重点实验室,.

【4】 Defective autophagy of pericytes enhances radiation-induced senescence promoting radiation brain injury,10.1093/neuonc/noae153,NEURO-ONCOLOGY,2024-08-07,IF=16.4,华中科技大学同济医学院附属同济医院,.

【5】 CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP-43 and Encoding A Novel TMEFF1-339aa Protein,10.1002/advs.202206732,Advanced Science,2023-04-23,IF=15.1,上海大学附属南通医院(南通市第六人民医院)大学,.

【11】 Antioxidative and antibacterial gallium (III)-phenolic coating for enhanced osseointegration of titanium implants via pro-osteogenesis and inhibiting osteoclastogenesis,10.1016/j.biomaterials.2023.122268,BIOMATERIALS,2023-08-07,IF=14,安徽中医药大学,.
【12】 Glucose-primed PEEK orthopedic implants for antibacterial therapy and safeguarding diabetic osseointegration,10.1016/j.biomaterials.2023.122355,BIOMATERIALS,2023-11-04,IF=14,四川大学华西医院,.
【13】 m6A-mediated gluconeogenic enzyme PCK1 upregulation protects against hepatic ischemia-reperfusion injury,10.1097/HEP.0000000000000716,HEPATOLOGY,2023-12-12,IF=13.5,中山大学附属第三医院,.
【14】 Etoposide-loaded layered double hydroxide achieves the best of both worlds: Simultaneous breast carcinoma inhibition and embryo protection via selectively regulating Caspase 3-GSDME pyroptosis pathway,10.1016/j.cej.2024.149485,CHEMICAL ENGINEERING JOURNAL,2024-02-09,IF=13.3,同济大学附属东方医院(上海市东方医院),.
【15】 The enhancing effect of DNA tetrahedron-based lactoferrin as an assembled adjuvant in immunotherapy,10.1016/j.cej.2025.159941,CHEMICAL ENGINEERING JOURNAL,2025-01-27,IF=13.3,有机电子与信息显示国家重点实验室,.
【16】 Organelle remodeling enhances mitochondrial ATP disruption for blocking neuro-pain signaling in bone tumor therapy,10.1016/j.cej.2025.159825,CHEMICAL ENGINEERING JOURNAL,2025-01-22,IF=13.3,复旦大学附属中山医院,.
【17】 The m6A methyltransferase Mettl3 deficiency attenuates hepatic stellate cell activation and liver fibrosis,10.1016/j.ymthe.2022.07.020,MOLECULAR THERAPY,2022-08-02,IF=12.91,中山大学附属第三医院,.
【18】 A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy,10.1016/j.biomaterials.2024.122574,BIOMATERIALS,2024-04-21,IF=12.8,同济大学附属东方医院(上海市东方医院),.
【19】 Polydopamine-Decorated PLCL Conduit to Induce Synergetic Effect of Electrical Stimulation and Topological Morphology for Peripheral Nerve Regeneration,10.1002/smtd.202200883,Small Methods,2023-01-03,IF=12.4,复旦大学附属中山医院,.
【20】 OTUB2 contributes to vascular calcification in chronic kidney disease via the YAP-mediated transcription of PFKFB3,10.7150/thno.98660,Theranostics,2025-01-01,IF=12.4,江苏省人民医院(南京医科大学第一附属医院),.

【6】 Sonic hedgehog-heat shock protein 90β axis promotes the development of nonalcoholic steatohepatitis in mice,10.1038/s41467-024-45520-8,Nature Communications,2024-02-12,IF=14.7,浙江大学医学院附属第四医院,.

【7】 P2Y14R activation facilitates liver regeneration via CREB/DNMT3b/Dact-2/β-Catenin signals in acute liver failure,10.1016/j.apsb.2025.01.004,Acta Pharmaceutica Sinica B,2025-01-19,IF=14.7,天然药物活性组分与药效国家重点实验室,.

【8】 A high-throughput Gaussia luciferase reporter assay for screening potential gasdermin E activators against pancreatic cancer,10.1016/j.apsb.2023.07.018,Acta Pharmaceutica Sinica B,2023-07-20,IF=14.5,天然药物活性组分与药效国家重点实验室,.

【9】 Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice,10.1002/advs.202406936,Advanced Science,2024-08-13,IF=14.3,南京中医药大学,.

【10】 CRISPR/Cas13 sgRNA-Mediated RNA–RNA Interaction Mapping in Live Cells with APOBEC RNA Editing,10.1002/advs.202409004,Advanced Science,2024-10-11,IF=14.3,中山大学附属第三医院,.

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