重组人表皮生长因子（EGF）

产品信息：
表皮生长因子（EGF）属于EGF家族，EGF与EGFR结合可以促进细胞增殖和分化，主要是表皮细胞、内皮细胞。EGF无糖基部位，非常稳定，耐热耐酸，广泛存在于体液和多种腺体中，主要由颌下腺、十二指肠合成，在人体的绝大多数体液中均已发现，在乳汁、尿液、精液中的含量特异性地增高，但在血清中的浓度较低。实验研究表明，EGF用于角膜损伤、烧烫伤及手术等创面的修复和愈合取得了很好的疗效，另外EGF在糖尿病足溃疡的治疗中也取得很好的效果。
别名:
Epidermal Growth Factor, Urogastrone, URG
英文描述:
EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant Human EGF is a 6.2 kDa globular protein containing 53 amino acid residues, including 3 intramolecular disulfide bonds.
氨基酸序列:
NSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELR
来源:
E.coli
 
保存条件：4℃保存6个月，-20℃保存一年或-80℃长期保存。
 
纯度&内毒素：
Greater than 95% by SDS-PAGE
gel and HPLC analyses.
Endotoxin Level<0.5EU/μg


The purity of rhEGF was determined by SDS-PAGE of reduced rhEGF and staining overnight with Coomassie Blue.