背景描述 | Panc 08.13 is an epithelial cell line that was isolated in 1995 from the pancreas of a White, 85-year-old, male patient with adenocarcinoma. This cell line was deposited by EM Jaffee and can be used in cancer research.The cell line exhibits a K-ras oncogene mutation at codon 12 where a GGT --> GAT mutation resulted in substitution of aspartic acid for glycine. The cells have a reported plating efficiency of 40%. |
年龄(性别) | 男性,85岁 |
组织来源 | 胰腺 |
细胞类型 | 肿瘤细胞 |
肿瘤类型 | 胰腺癌细胞 |
生物安全等级 | 1 |
倍增时间 | 20.0 hours (PubMed=9612602); 117 hours (PubMed=25984343) |
致瘤性 | Yes; Yes, forms tumors in nude or SCID mice |
抗原表达情况 | MHC class I +; MHC class II - |
基因表达情况 | cytokeratin 7; cytokeratin 18 |
保藏机构 | ATCC; CRL-2551 |