SkinEthicTM HCE是人类角膜角质形成细胞株在聚碳酸脂滤膜上,由化学定制培养基经过气液培养而成的重建人类角膜模型。该重建模型具有良好分层和完整结构的上皮组织,包含基底、翼状和粘液生成细胞,在结构、形态和功能方面接近于在体的人类角膜。它可用于体外眼刺激性(OECD TG492 标准模型),基因、蛋白组学,细菌粘附等的检测和研究。
SkinEthicTM HCE model is composed of transformed human corneal keratinocytes cultivated on an inert polycarbonate filter at the air liquid interface in a chemically defined medium. The reconstructed tissue forms a stratified and well organized epithelium which is structurally, morphologically and functionnally similar to the human cornea with presence of basal, wing and mucus production cells. The model is widely used in the test and research in vitro of eye irritation (reference model of OECD-TG492), OMICS, Bacterial adhesion, etc…