DNA Pulldown 试剂盒

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北京擎科生物科技股份有限公司
18622657960 00000000
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Last Updated 2025-08-12 15:19

DNA Pulldown 试剂盒

产品简介:DNA pulldown技术利用生物素标记的DNA作为诱饵分子,富集DNA结合蛋白(转录因子、共调节因子、DNA修复酶等)的实验技术。DNA pulldown技术是使生物素标记的DNA探针与细胞全蛋白提取液孵育,形成DNA蛋白质复合物。该复合物可被链霉亲和素标记的磁珠结合并分离纯化。洗脱获取到的复合物,可以用于western blot实验或蛋白质质谱实验。
产品应用:
♦ 特定基因的转录因子筛选研究;
♦ 转录因子靶向结合特定基因的验证研究;
♦ 转录因子结合区域研究;
♦ DNA修饰(m5C等)结合修饰酶、去修饰酶及读取酶研究。
产品特点:
♦ 探针材料:使用DNA探针开展实验,准备周期短且特殊物种不受没有抗体的限制;
♦ 流程简便:DNA探针总量大可以富集具备结合功能的蛋白;
♦ 样本适用广:适用于动物、植物、真菌等细胞生物;
♦ 时间周期短:整个实验流程<3h;
♦ 适配WB及MS检测:洗样品适配western blot鉴定。

Company Name 北京擎科生物科技股份有限公司
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