Language
| CBP74098 | |
| I. Background | |
| Established from an ascites of a tumour induced in a male mouse by intraperitoneal injection of Abelson Leukaemia Virus (A-MuLV). Cells will pinocytose neutral red and phagocytose zymosan. Cells capable of antibody dependent lysis of sheep erythrocytes and tumour targets. Growth inhibited by LPS. | |
| II. Description | |
| The ISRE Reporter kit is designed for monitoring the activity of Type I interferon-induced JAK/STAT signaling pathway in the cultured cells. | |
| III. Introduction | |
| Host Cell: | Raw264.7 |
| Expressed gene: | ISRE |
| Stability: | 32 passages(in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+200ug/ml zeocin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| IV. Description of Host Cell Line | |
| Organism: | Mus musculus, mouse |
| Tissue: | Abelson murine leukemia virus-induced tumor; ascites |
| Disease: | Abelson murine leukemia virus-induced tumor |
| Morphology: | Monocyte/macrophage |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
| Figure 1. Dose Response of 2'3-cGAMP in RAW264.7 ISRE-Luc Cells , the EC50 was 8.2μM. | |
