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Trilink CleanCap® Reagent AG - (N-7113)产品介绍
mRNA共转录加帽产品CleanCap® Reagent AG，m7G(5')ppp(5')(2'OMeA)pG
产品描述：
CleanCap® Reagent AG是Trilink专利加帽产品，Trilink N-7113体外共转录，5’端加帽形成cap1结构。CleanCap的加帽效率可以达到98%。请注意：Trilink推荐尽可能使用CleanCapAG，CleanCap AG需要AG启动子。通常情况下，CleanCap AG的加帽效率>90%。和CleanCap AG不同，CleanCap GG (cat. no. N-7133 or N-7433) 的专利效率和产量和ARCA类似。
产品信息：
| 产品货号 | N-7113 |
| 纯度 | ≥95% by AX-HPLC |
| 消光系数 | 30,539 Lmol-1cm-1 at 255 nm |
| 分子式 | C32H43N15O24P4 (游离酸) |
| 分子质量 | 1145.60 g/mole (游离酸) |
| 盐形式 | Na+ |
| 浓度 | 100 mM |
| 溶液组分 | 水 |
| 推荐的储存温度 | -20°C 或者以下 |
| 其他名称 | CleanCap® Reagent AG for co-transcriptional capping of mRNA,m7G(5')ppp(5')(2'OMeA)pG |
| 应用 | CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases |
| 主链 | 5'-5'-三磷酸 |
| 碱基类似物 | 腺苷酸，鸟苷酸 |
| 核苷酸种类 | 帽类似物 |
产品规格如下：
| 供应商 | 产品编号 | 产品名称 | 规格 |
| TriLink | N-7113-1 | CleanCap Reagent AG, 1 umole | 1 umol |
| TriLink | N-7113-10 | CleanCap Reagent AG, 10 umoles | 10 umol |
| TriLink | N-7113-100 | CleanCap Reagent AG, 100 µmole | 100 umol |
| TriLink | N-7113-5 | CleanCap Reagent AG, 5 umole | 5 umol |
文献引用；
Jiang, T;Henderson, JM;Coote, K;Cheng, Y;Valley, HC;Zhang, XO;Wang, Q;Rhym, LH;Cao, Y;Newby, GA;Bihler, H;Mense, M;Weng, Z;Anderson, DG;McCaffrey, AP;Liu, DR;Xue, W; . Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope
Tusup, M;L . mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma
Yu, D;Kaur, G;Blumenthal, RM;Zhang, X;Cheng, X; . Enzymatic characterization of three human RNA adenosine met-hyltransferases reveals diverse substrate affinities and reaction optima
Hashimoto, K;Kodama, A;Ohira, M;Kimoto, M;Nakagawa, R;Usui, Y;Ujihara, Y;Hanashima, A;Mohri, S; . Transient induction of cell cycle promoter Fam64a improves cardiac function through regulating Klf15-dependent cardiomyocyte differentiation in mice
更多详情请联系TriLink中国授权代理商——欣博盛生物
