Sigma货号73594-100G-F乙酸铵(Ammonium acetate)上海睿安生物13611631389

Sigma货号73594-25G-F乙酸铵(Ammonium acetate)上海睿安生物13611631389

乙酸铵

LiChropur^™,eluent additive for LC-MS

说明

一般描述:乙酸铵以白色晶体的形式存在。它时以醋酸和氨为原料制备，经中和至pH 7.0。它被广泛应用于分析化学、医药、纺织染色等领域。

应用:乙酸铵已可用于制备UPLC-MS/MS洗脱液和HPLC-MS/MS洗脱液，以比较9种药物化合物在水环境样品中的基质效应。它还被用作添加剂，以提高MALDI-MS对磷酸肽的检测。

法律信息:ASTM is a registered trademark of American Society for Testing and Materials,LiChropur is a trademark of Merck KGaA,Darmstadt,Germany.

同行评审论文(部分文献)

Dale L. PerryHandbook of Inorganic Compounds, 17-17 (1995)Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts.Asara JM, Allison J.Journal of the American Society For Mass Spectrometry, 10(1), 35-44 (1999)Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts.J M Asara et al.Journal of the American Society for Mass Spectrometry, 10(1), 35-44 (1999-01-15)Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) has been used successfully to detect phosphorylation sites in proteins. Applications may be limited by the low response of phosphopeptides compared to nonphosphorylated peptides in MALDI MS. The addition of ammonium salts toComparison of matrix effects in HPLC-MS/MS and UPLC-MS/MS analysis of nine basic pharmaceuticals in surface waters.Jet C Van De Steene et al.Journal of the American Society for Mass Spectrometry, 19(5), 713-718 (2008-03-18)When developing an LC-MS/MS-method matrix effects are a major issue. The effect of co-eluting compounds arising from the matrix can result in signal enhancement or suppression. During method development much attention should be paid to diminishing matrix effects as muchComparison of matrix effects in HPLC-MS/MS and UPLC-MS/MS analysis of nine basic pharmaceuticals in surface waters.Van De Steene JC, Lambert WE.Journal of the American Society For Mass Spectrometry, 19(5), 713-718 (2008)