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1 Sample Kit when tested in 2 strains (TA98, TA100), +/- S9, 3 Replicates, 6 Doses, Positive & Negative Controls: Strains, Media, Ampicillin, Booster, PB/ßNaphtoflavone induced rat liver S9, Controls. Not included in the kit: S9 cofactor solutions, microplates
Description
Ames MPF 98/100 is a miniaturized, ready to use Ames Test kit in a liquid microplate format. It includes all reagents necessary to run 1 sample with strains TA98 and TA100: 1 vial each of semisolid TA98, TA100, plus Booster, Growth -, Exposure -, Reversion Indicator Media, Ampicillin, Positive Controls, lyophilized Post-Mitochondrial Supernatant S9 from Aroclor 1254 induced rat liver. Not included in the kit are plastic ware and S9 Cofactor solutions.
Published data about several tested compounds with this liquid microplate Ames Test are available under Database or Publications on this homepage.
The kits are quality controlled and do not need an inhouse quality control (phenotypes) like the agar Assay in petri dishes.
Service analytics for early drug discovery with test compound of 11 mg / strain (+/- S9) with the Ames MPF assay system is available as well under GLP and non GLP conditions, please contact info@xenometrix.ch.
Characteristics
- Quality controlled products: all products of the kit
- Certificate of Analysis: Provided
- Excel Calculation Sheet to support Data Interpretation
- Comparison with agar late test: Corresponds to 2 x 480 agar plates.
- Enough Material to process Strains individually
- Shipped at Room Temperature from external Storage in Germany
- High sensitivity and excellent correlation with agar plate test (see database and publications on this homepage)
- 4 times less test compound as compared to the agar plate test
- Less hands-on-time and simultaneous processing of several replicates
- Automation available - High throughput format
- 3Rs - 12 fold less consumption of rat liver liver S9, less test animals
- Less error prone due to easy colorimetric read-out
- Waste - Significant less plastic waste and thus reduced contaminated waste in Environment
- Technology Transfer available
