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Affinite 个人型SPR分子互作分析仪

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普瑞麦迪(北京)实验室技术有限公司
010-51668388-8009
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Last Updated 2025-08-08 22:34

Affinite 个人型SPR分子互作分析仪

产品简介

 

P4SPR凭借紧凑的设计,您可以通过减少样品制备时间和在工作台或现场使用SPR来更快地进行分析测试。我们独特的技术不仅可以检测和监测生物分子,如多肽、蛋白、核酸等各种生物分子的相互作用,还可以测量结合动力学,且设备方便携带,还可以用于户外现场中的农药残留、微量药物、污染物等环境检测。

关于Affinité Instruments公司

*Affinité Instruments 2015年由加拿大蒙特利尔大学知名教授Jean-François Masson创办

*基于Jean-François Masson教授十数年在SPR领域积累的深厚经验, Affinité Instruments 成功开发并商业化基于  SPR原理的新一代非标记分子相互作用分析仪P4SPR,助力基础研究

 

 

 

Affinité Instruments公司部分合作伙伴



产品优势

 

-基于SPR原理, 实时、 无标记、检测相互作用

-适用于小分子化合物、核酸、多肽、蛋白、抗体、脂类、多糖、纳米颗粒、病毒、微生物、细胞等各种类型样品

-10分钟内完成测试,获得特异性、亲和力、动力学、浓度等数据

-可检测各种在复杂溶液之中完成测量,比如血液、牛奶、细胞裂解液等
-可手动进样或者进样泵,操作简单,无需维护
-可与其它仪器( HPLC,MS等)联合使用
-价格适中,单个实验室即可负担
-仪器小巧, 易于携带
-仪器稳定、可用于户外环境现场检测

 

技术参数

检测原理

实时无标记表面等离子共振(SPR)

光源及探测器

波长扫描多色LED光源; 550-750 nm探测器

传感器

高均一金薄膜传感器

折射率范围

1.333 - 1.390 RIU

结合速率(Ka)

103 - 109 M-1s-1

解离速率(Kd)

10-6 - 10-1 s-1

亲和力

pM-mM

检测通道

4通道:3+1;1x4

样品体积

10-200μl
进样方式手动进样或蠕动泵进样
检测时间10分钟
软件
LabVIEW,可输出兼容TraceDrawer, Origin, MatLab, Excel的原始数据
硬件参数
尺寸≤175 x 155 x 55 mm,重量< 1.3 Kg
应用领域

发表文献

* Title Journal Journal details Year Area Document Column Hybridization conditions of oligonucleotidecapped gold nanoparticles for SPR sensing of
microRNA. Biosensors and Bioelectronics, 2018 Volume 109, Pages 230Z236
* Tracking silent hypersensitivity reactions to asparaginase during leukemia therapy using single-chip indirect plasmonic and fluorescence
immunosensing. ACS Sensors. 2017 2A12B{1761Z1766.
* Gomez-Diaz C, Bargeton B, Abuin L, Bukar N, Reina JH, Bartoi T, Graf M, Ong H, Ulbrich MH, Masson JF, Benton R. A CD36 ectodomain mediates
insect pheromone detection via a putative tunnelling mechanism. Nat Commun. 2016 Jun 15;7:11866.
* Chehboun S, Labrecque-Carbonneau J, Pasquin S, Meliani Y, Meddah B, Ferlin W, Sharma M, Tormo A, Masson JF, Gauchat JF. Epstein-Barr virusinduced gene 3 (EBI3) can mediate IL-6 trans-signaling. J Biol Chem. 2017 Apr 21;292(16):6644-6656.
* Brulé T, Granger G, Bukar N, Deschênes-Rancourt C, Havard T, Schmitzer AR, Martel R, Masson JF. A field-deployed surface plasmon resonance
(SPR) sensor for RDX quantification in environmental waters. Analyst. 2017 Jun 21;142(12):2161-2168.
* Aubé A, Campbell S, Schmitzer AR, Claing A, Masson JF. Correction: Ultra-low fouling alkylimidazolium modified surfaces for the detection of HER2
in breast cancer cell lysates. Analyst. 2017 Aug 7;142(16):3011.
* Charbonneau DM, Aubé A, Rachel NM, Guerrero V, Delorme K, Breault-Turcot J, Masson JF, Pelletier JN. Development of Escherichia coli
Asparaginase II for Immunosensing: A Trade-Off between Receptor Density and Sensing Efficiency. ACS Omega. 2017 May 31;2(5):2114-2125.
* McKeating KS, Aubé A, Masson JF. Biosensors and nano biosensors for therapeutic drug and response monitoring. Analyst. 2016 Jan
21;141(2):429-49.
* Yockell-Lelièvre H, Bukar N, McKeating KS, Arnaud M, Cosin P, Guo Y, Dupret-Carruel J, Mougin B, Masson JF. Plasmonic sensors for the
competitive detection of testosterone. Analyst. 2015 Aug 7;140(15):5105-11.
* Zhao SS, Bukar N, Toulouse JL, Pelechacz D, Robitaille R, Pelletier JN, Masson JF. Miniature multi-channel SPR instrument for methotrexate
monitoring in clinical samples. Biosens Bioelectron. 2015 Feb 15;64:664-70.
* ........

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